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SUBOXONE® (buprenorphine and naloxone) Sublingual Film (CIII) & Subutex are prescription medicine indicated for treatment of opioid dependence and should be used as part of a complete treatment plan to include counseling and psychosocial support. By suppressing withdrawal symptoms and reducing cravings, SUBOXONE Film can help people with opioid dependence take steps to manage their condition so they can focus on rebuilding their lives.